The Mayo Clinic Lipid Panel, Fasting, Serum (LPSC) test is a blood test that measures cholesterol and triglyceride levels. High levels of cholesterol and triglycerides can increase the risk of heart disease, stroke, and other cardiovascular problems. The LPSC test measures several components, including total cholesterol, LDL (bad) cholesterol, HDL (good) cholesterol, and triglycerides. A healthcare provider may order this test to evaluate a patient's risk for heart disease or to monitor the effectiveness of lipid-lowering medications. Fasting is required for at least 9-12 hours before the test to ensure accurate results.